mediastinitis
Advices
| Priority | Medication | Remarks | 
|---|---|---|
| 
                                              Medication: amoxicilline + clavulaanzuur iv 1000/200mg 3dd 2 to 6 weeks + 
                                                                            amoxicilline iv 1000mg 3dd 2 to 6 weeks  | 
                    
                                               
                          Remarks: 
                           
                                          SWAB remarks Na perforatie tr. digestivus: community-accquired. Om en om Augmentin/amoxicilline, dus 3 dd Augmentin 1200 mg en 3 dd amoxicilline 1000 mg  | 
                  |
| 
                                              Medication: cefuroxim iv 1500mg 3dd 2 to 6 weeks + 
                                                                            metronidazol iv 500mg 3dd 2 weeks  | 
                    
                                               
                          Remarks: 
                           
                                          SWAB remarks Na perforatie tr. digestivus: na manipulatie of ingreep  | 
                  |
| 
                                              Medication: flucloxacilline iv 1000mg 6dd 2 to 6 weeks or 
                                                                            flucloxacilline iv loading dose 1000mg, 6000mg continuous per 24 hours 2 to 6 weeks  | 
                    
                                               
                          Remarks: 
                           
                                          SWAB remarks Postoperatief na sternotomie  | 
                  
Sources
- 
          
                          Pubmed.gov publication # 31306791
              
              
            
                          
Pastene B, et al. Mediastinitis in the intensive care unit patient: a narrative review. Clin Microbiol Infect. 2020 Jan;26(1):26-34.
 
TDM Alert
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
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Metadata
            Swab vid: G-8519.6
            Updated: 03/28/2023 - 17:21
            Status: Published
          
          
General comments
Op geleide van kweek wordt therapie aangepast
Bij sepsis toevoegen eenmalig tobramycine 7 mg/kg